"We Make Families"- Blog

Reducing risk and increasing opportunity through CGH

Early pregnancy loss, though common, can by emotionally devastating. As many as 10 to 20 percent of known pregnancies end in miscarriage.

At least half of the time, those miscarriages occur because the fetus isn’t developing normally due to extra or missing chromosomes.

While all pregnancy loss is difficult, it can be especially difficult for parents who have struggled to conceive and have finally conceived through In Vitro Fertilization (IVF). IVF is an intense process, and losing a pregnancy after successfully navigating the physical and financial demands can seem particularly crushing.

What if you could reduce the chance of miscarrying after IVF, and increase the chances of a successful pregnancy? A test known as Comparative Genomic Hybridization (CGH) holds the key.

Using this technique, our doctors identify which embryos have the full 23 pairs of chromosomes, and only transfer those embryos for implantation.

The result? Studies show that miscarriage rates drop to around five percent, while pregnancy rates jump to 60 -70 percent. CGH also identifies other genetic conditions, such as Down’s syndrome.

Comparative Genomic Hybridization is a tool used in Preimplantation Genetic Screening (PGS). PGS is an important option offered by New England Fertility. PGS is recommended for parents who have no known genetic abnormalities, as well as patients who meet any of the following conditions:

  • Female partner age 38 or older
  • Couples interested in a single embryo transfer
  • Couples interested in gender selection
  • History of pregnancy loss (recurrent miscarriage)
  • History of failed IVF/implantation failure

PGS is safe for embryos, and does not impact viability.

It’s important to note that PGS doesn’t replace the usual prenatal testing recommended during pregnancy, and those options should also be discussed with your doctor.

Interested in learning more about CGH, or other ways we work with you to maximize opportunities for the best possible outcome? Request a consultation today.

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